Research towards Treatment
“Data sharing is essential for expedited translation of research results into knowledge, products, and procedures to improve human health. ”
— National Institute of Health
Among the main goals of the Human Genome Project (HGP) was to develop new, better and cheaper tools to identify new genes and to understand their function.
Aligned with Project 8p’s mission of translational research is our ability to fund and welcome partnerships to take clinical action. With quality data sharing, transparency, and free access to our iPSC lines and open-access mice models and organisms, we encourage researchers around the world to help us discover clinically relevant, medically actionable, stretches of DNA that are the key to helping individuals affected by genetic disease, and the “future of medicine” for 8p disorders.
We invite researchers to help us identify the specific priority genes and which symptoms they are associated with, understand the cause of the genetic mutation, and develop a treatment plan and possible prevention of this disorder.
We are pragmatic and impatiently patient about the unknown timeline; therefore, we want to start now and be ready to take advantage of the future of genome medicine.
We are eager to be a strategic partner at the onset of assessing markets for drug development and determining feasibility. The US FDA and international regulatory agencies are incentivizing orphan drug development in many ways that allow expedited approval, greater flexibility in clinical trials, and more innovation in the process.
Grant Indirect Cost Policy
The key differentiating factor between “direct” and “indirect” costs is whether the cost is specifically required for the project or program to meet its objectives:
Direct costs are expenses directly incurred for the specific project or program being funded. Examples include salaries for program staff, travel expenses, materials, consultants required to execute the grant. Expenses like these would not be incurred if the project or program did not exist.
Indirect costs are overhead and administration expenses necessary to support an organization’s general operation, which are thus shared across projects or programs.
Examples include rent and utilities, office furniture, computers and information systems, and the costs of functions like development, finance and accounting, IT, HR, and legal. Expenses like these would be incurred in some amount with or without a specific project or program grant. Indirect costs are those for activities or services that benefit more than one project. Their precise benefits to a specific project are often difficult or impossible to trace.
Policy For Universities: Project 8p recognizes that grant award recipients may have overhead costs that are not directly attributable to the proposed project but are necessary to carry out the proposed project. Project 8p will not fund indirect costs, and therefore can only make grants to researchers and institutions that can absorb the indirect costs of the project. If an indirect cost estimate can be reasonably and transparently attributed to costs fairly associated with the program or project in question, we may make an exception and accept an indirect cost amount up to 10%. Grantees should discuss such an exception prior to submitting proposals.