We were thrilled to host Drs Felix Wong and Max Wilson, the founders of Integrated Biosciences, on the February 8p Research Roundtable. Integrated Bioscience is a biotech company with a unique drug screening platform that enables discovery of small molecules that regulate the integrated stress response (ISR) pathway. In short, the team at Integrated Biosciences (IB) is able to artificially induce phantom stress inside of cells without actually exposing the cells to any harmful stressors.
This setup allows IB to identify small molecules that target the ISR sensor proteins directly rather than an indirect downstream or maladaptive response. They have already identified novel small molecules that can amplify or mute the ISR pathway. They also have a proprietary in-house library of several hundred thousand novel compounds.
